Coumarins and derivatives
SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES 7-METHOXYCOUMARIN-4-ACETYL-GL
NC3736128 7-METHOXYCOUMARIN-4-ACETYL-GL
Apexbio Technology LLC Coumarin-3-carboxylic Acid 531-81-7 100mg
Coumarin-3-carboxylic Acid is a coumarin-derived small molecule commonly applied as an investigative tool in biomedical research focusing on signal pathway regulation It is utilized to modulate enzymatic activities and cellular signaling pathways Coumarin-3-carboxylic Acid s biological activity has been studied in the context of its lanthanide complexes for inhibitory effects on cell growth in K-562 cell lines In cell-based studies it demonstrates antiproliferative activity in K-562 cells Based on these pharmacological properties Coumarin-3-carboxylic Acid holds research potential in elucidating biological mechanisms underlying hematologic malignancies and related diseases
Cayman Chemical ANTIBODY CoumarIn 6 1g
An acid-sensitive fluorescent probe; upon protonation, it displays a shift in emission maxima from 410 nm to 510 nm upon excitation at 157 nm; has been commonly used in photolithography
eMolecules 20300-59-8 | 7-Methoxy-2-oxochromene-3-carboxylic acid | Combi-Blocks | MFCD00452770 | 220.180 | C11H8O5 | 98.000 | COc1ccc2cc(C(O)=O)c(=O)oc2c1 | 1g | 267167713
7-Methoxy-2-oxochromene-3-carboxylic acid | Combi-Blocks | 20300-59-8 | MFCD00452770 | 220.180 | C11H8O5 | 98.000 | COc1ccc2cc(C(O)=O)c(=O)oc2c1 | 1g | 267167713
Medchemexpress LLC 3-aminocoumarin (3-aminochromen-2-one) | 1635-31-0 | MFCD00016965 | 99.2% | 161.16 | C9H7NO2 | 250 MG
3-Aminocoumarin (3-aminochromen-2-one) is a coumarin-derived organic intermediate used in research and chemical synthesis. It functions as a building block for the preparation of metal complexes and other functionalized coumarin derivatives, and is supplied as a laboratory research reagent with recommended storage instructions to preserve stability.
- Coumarin-derived intermediate for organic synthesis.
- Suitable for synthesis of metal complexes and functionalized derivatives.
- Molecular formula C9H7NO2; molecular weight 161.16 g/mol.
- Recommended storage: solid at 4°C, protect from light; solutions -80°C (6 months) or -20°C (1 month).
- Provided as a research reagent; follow appropriate safety and handling procedures.
Apexbio Technology LLC 7-Amino-4-(trifluoromethyl)coumarin 53518-15-3 500mg
7-Amino-4-trifluoromethyl coumarin (CAS 53518-15-3) is a small-molecule antagonist targeting serotonin receptor subtype 1E (HTR1E) galanin receptor 2 (GALR2) and gamma receptor subtype 2 (GalR2) It is designed to antagonize these receptors thereby modulating receptor-mediated signaling pathways 7-Amino-4-trifluoromethyl coumarin exerts its biological activity primarily through receptor antagonism and inhibition of hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4) enzymatic activity In biochemical assays it demonstrates inhibitory activity toward HSD17B4 with reported bioactivity at approximately 21 M Based on these pharmacological properties 7-Amino-4-trifluoromethyl coumarin holds research potential in the investigation of protease activity receptor-mediated signaling and metabolic enzyme regulation
Cayman Chemical 3-Cyno-7-ethoxycoumarIn 50mg
A fluorogenic CYP450 substrate; a substrate for CYP1A1 and CYP1A2; metabolized to a lesser extent by CYP2D6 and CYP2C19; metabolized to 3-cyano-7-hydroxycoumarin and its fluorescence can be used to quantify CYP450 isoform activity
Sigma Aldrich Fine Chemicals Biosciences 7-Diethylamino-4-methylcoumarin 99% | 91-44-1 | MFCD00006864 | 100G
7-Diethylamino-4-methylcoumarin 99% | Purity: 99% | Mol Wt: 231.29 | 91-44-1 | MFCD00006864 | 100G
Selleck Chemical LLC 7-Methoxy-4-methylcoumarin S4780-25mg
7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label 7-Methoxy-4-methylcoumarin has an antimicrobial activitiy against both gram positive and gram negative bacterial stains 4-Methylherniarin displays good activity against B subtilis and S sonnei with IC50 of 11 76 g/ml and 13 47 g/ml respectively
Cayman Chemical 3-Cyno-7-ethoxycoumarIn 5mg
A fluorogenic CYP450 substrate; a substrate for CYP1A1 and CYP1A2; metabolized to a lesser extent by CYP2D6 and CYP2C19; metabolized to 3-cyano-7-hydroxycoumarin and its fluorescence can be used to quantify CYP450 isoform activity
Medchemexpress LLC Coumarin-C2-exo-BCN | 2488174-17-8 | 95.7% | 479.57 g·mol⁻¹ | C27H33N3O5 | 10 MG
Coumarin-C2-exo-BCN is a coumarin-derived fluorescent dye functionalized with an exo-BCN strained alkyne for bioorthogonal labeling via strain-promoted alkyne-azide cycloaddition (SPAAC). It is intended for catalyst-free conjugation to azide-containing biomolecules to generate fluorescent triazole-linked products.
- Fluorescent coumarin scaffold for sensitive detection.
- exo-BCN strained alkyne enables catalyst-free SPAAC with azides.
- Used to prepare fluorescent conjugates and label azide-containing biomolecules.
- Supplied as a solid with reported purity of ~95.7%.
Medchemexpress LLC 6-Bromocoumarin | 19063-55-9 | 225.04 | 5 G
6-Bromocoumarin is a potential anti-bacterial agent that shows no inhibition against 17β-HSD1 and exhibits affinity for α and β estrogen receptors. It is supplied as a white to off-white solid with a purity of 98.51% and a molecular weight of 225.04.
- Potential anti-bacterial agent
- Exhibits affinity for α and β estrogen receptors
- Solid appearance, white to off-white color
- Stable under recommended storage conditions
- For research use only
Medchemexpress LLC Coumarin-d4 | 185056-83-1 | 150.17 | 5 MG
Coumarin-d4 is the deuterium labeled version of Coumarin, which is the primary bioactive ingredient found in Radix Glehniae, also known as Beishashen in China. It exhibits various pharmacological activities, including anticancer, anti-inflammation, and antiviral properties. Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs. It is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC 7-hydrazinyl-4-methyl-2H-chromen-2-one | 113707-87-2 | MFCD09999551 | 97.1% | 190.20 | C10H10N2O2 | 100MG
Coumarin hydrazine is a fluorescent chemical probe used to label protein- and lipid-bound carbonyls in cells and biochemical assays. It reacts with aldehydes and ketones to form fluorescent hydrazones, producing a measurable signal suitable for live-cell and in vitro labeling when handled protected from light (λex = 420-450 nm; λem ≈ 468 nm).
- Fluorogenic probe for labeling protein- and lipid-bound carbonyls.
- Reacts with aldehydes and ketones to form fluorescent hydrazones.
- Excitation 420-450 nm; emission ≈468 nm.
- Molecular formula C10H10N2O2; molecular weight 190.20.
- Purity 97.1%; supplied as a 100 mg solid.
- Protect from light; in solvent store at -80°C for up to 6 months or at -20°C for up to 1 month.